2022
Berners-Lee A*, Shtrahman E*, Grimaud J, Murthy VN. 2022. Learning-dependent evolution of odor mixture representations in piriform cortex. bioRxiv. doi:
Ganga Prasath S, Mandal S, Giardina F, Kennedy J, Murthy VN, Mahadevan L. 2021. Dynamics of cooperative excavation in ant and robot collectives. eLife. doi.org/10.7554/eLife.79638 [Press: MCB News]
Martiros N, Kim SE, Kapoor V, Murthy VN. 2022. Distinct representation of cue-outcome association by D1 and D2 neurons in the ventral striatum’s olfactory tubercle . eLife.
Masset P, Zavatone-Veth J, Connor, JP, Murthy VN, Pehlevan C. 2022. Population geometry enables fast sampling in spiking neural networks. bioRxiv. d
Lauer J et al. 2022. Multi-animal pose estimation, identification and tracking with DeepLabCut. Nat. Methods. 19:496–504. doi:10.1038/s41592-022-01443-0
Jayakumar S, Murthy VN. 2022. A new angle on odor trail tracking. Proc. Natl. Acad. Sci. USA. 19:e2121332119. doi:10.1073/pnas.2121332119
2021
Martiros N, Kim SE, Kapoor V, Murthy VN. 2021. Distinct representation of cue-outcome association by D1 and D2 neurons in the olfactory striatum. bioRxiv.
Reddy G, Murthy VN, Vergassola M. 2022. Olfactory sensing and navigation in turbulent environments. Annu Rev Condens Matter Phys. 13:191-213. doi:10.1146/annurev-conmatphys-031720-032754.
Lau CG, Zhang H, Murthy VN. 2021. Deletion of TrkB in parvalbumin interneurons alters cortical neural dynamics. J Cell Physiol. doi.org/10.1002/jcp.30571
Grimaud J, Dorrell W, Pehlevan C, Murthy VN. 2021. Bilateral alignment of receptive fields in the olfactory cortex. bioRxiv. doi: 10.1101/2020.02.24.960922.
2020
Zak JD, Reddy G, Vergassola M, Murthy VN. 2020. Antagonistic odor interactions in olfactory sensory neurons are widespread in freely breathing mice. Nat. Commun. 11(1):3350 doi: 10.1038/s41467-020-17124-5. [Press: MCB News]
Zak JD, Wallace JL, Murthy VN. 2020. How neuroscience labs can limit their environmental impact. Nat. Rev. Neurosci. doi: 10.1038/s41583-020-0311-5. [Press: MCB News]
Millman DJ, Murthy VN. 2020. Rapid learning of odor-value learning in the olfactory striatum. J. Neurosci . pii: JN-RM-2604-19. . [Press: MCB News]
Wallace JL, Lord J, Dissing-Olesen L, Stevens B, Murthy VN. 2020. Microglia depletion disrupts normal functional development of adult-born neurons in the olfactory bulb. eLife 9. pii: e50531. doi: 10.7554/eLife.50531. [Press: MCB News]
2019
Zak JD, Reddy G, Vergassola M, Murthy VN. 2019. Antagonistic odor interactions in olfactory sensory neurons are widespread in freeling breathing mice. bioRxiv preprint. doi: 10.1101/847525.
Nelson AC*, Kapoor V*, Vaughn E, Gnanasegaram JA, Rubinstein ND, Murthy VN, Dulac C. 2019. Molecular and circuit architecture of social hierarchy. bioRxiv preprint. doi: 10.1101/838664. * co-first author
Chae H, Kepple DR, Bast WG, Murthy VN, Koulakov AA, Albeanu DF. 2019. Mosaic representations of odors in the input and output layers of the mouse olfactory bulb. Nat Neurosci. 22(8):1306-1317. doi: 10.1038/s41593-019-0442-z [Press: EurakAlert, MedicalXpress]
Platel JC, Angelova A, Bugeon S, Wallace J, Ganay T, Chudotvorova I, Deloulme JC, Béclin C, Tiveron MC, Coré N, Murthy VN, Cremer H. 2019. Neuronal integration in the adult mouse olfactory bulb is a non-selective addition process. eLife. 8. pii: e44830. doi: 10.7554/eLife.44830.
2018
Albeanu DF*, Provost AC*, Agarwal P*, Soucy ER, Zak JD, Murthy VN. 2018. Olfactory marker protein (OMP) regulates formation and refinement of the olfactory glomerular map. Nat Commun. 9(1):5073. doi:10.1038/s41467-018-07544-9. (*joint first authors)
Draft RW*, McGill MR*, Kapoor V, Murthy VN. 2018. Carpenter ants use diverse antennae sampling strategies to track odor trails. J Exp Biol. pii:jeb.185124. doi: 10.1242/jeb.185124. (*joint first authors) [Press: J Exp Biol, Harvard MCB; New York Times; ScienceTake video]
Mathis A, Mamidanna P, Cury KM, Abe T, Murthy VN, Mathis MW#, Bethge M#. 2018. DeepLabCut: markerless pose estimation of user-defined body parts with deep learning. Nat Neurosci. 20. doi: 10.1038/s41593-018-0209-y. (#joint senior authors) [Press: Nature Neuroscience, The Atlantic, Phys.org, Schwäbishes Tagblatt, Harvard Gazette]
Zak JD, Grimaud J, Li RC, Lin CC, Murthy VN. 2018. Calcium-activated chloride channels clamp odor-evoked spike activity in olfactory receptor neurons. Sci Rep. 8(1):10600. doi: 10.1038/s41598-018-28855-3.
Grimaud J, Murthy VN. 2018. How to monitor the breathing of laboratory rodents: a review of the current methods. J Neurophysiol. doi: 10.1152/jn.00708.2017.
Reddy G*, Zak JD*, Vergassola M#, Murthy VN#. 2018. Antagonism in olfactory receptor neurons and its implications for the perception of odor mixtures. eLife 7:e34958 doi: 10.7554/eLife.34958 (* joint first authors; #joint senior authors) [Press: Harvard MCB, UCSD News ]
Galliano E, Franzoni E, Breton M, Chand AN, Byrne DJ, Murthy VN, Grubb, MS. 2018. Embryonic and postnatal neurogenesis produce functionally distinct subclasses of dopaminergic neuron. eLife 7. pii: e32373. doi: 10.7554/eLife.32373.[Press: Harvard MCB, King’s College London]
Wuttke TV, Markopoulos F, Padmanabhan H, Wheeler AP, Murthy VN, Macklis JD. 2018. Developmentally primed cortical neurons maintain fidelity of differentiation and establish appropriate functional connectivity after transplantation. Nat Neurosci. 21:517-529. doi: 10.1038/s41593-018-0098-0. [Press: The Hindu]
2017
Murthy VN, Rokni, D. 2017. Processing of Odor Mixtures in the Mammalian Olfactory System. J. Indian Inst. Sci. 97:415-421.
Li Y, Mathis, A, Grewe BF, Osterhout JA, Ahanonu GB, Schnitzer, MJ, Murthy VN, Dulac, C. 2017. Neuronal representation of social information in the medial amygdala of awake behaving mice. Cell 171:1176-1190.e17. doi: 10.1016/j.cell.2017.10.015 [Press: HHMI, Science Daily, Harvard MCB]
Wallace JL*, Wienisch M*#, Murthy VN#. 2017. Development and refinement of functional properties of adult-born neurons. Neuron 96:883-896.e7. doi: 10.1016/j.neuron.2017.09.039 (* joint first authors; #joint senior authors) [Press: Harvard MCB]
Mazo C, Grimaud J, Shima Y, Murthy VN*, Lau CG*. 2017. Distinct projection patterns of different classes of layer 2 principal neurons in the olfactory cortex. Sci Rep 7:8282 doi:10.1038/s41598-017-08331-0 (*joint senior authors)
2016
Mathis A*, Rokni D*, Kapoor V, Bethge M and Murthy VN. 2016. Reading out olfactory receptors: feedforward circuits detect odors in mixtures without demixing. Neuron. 91:1–14. (* joint first authors) [Press: Harvard Gazette, Harvard MCB, Wissenschaftler]
Wienisch M and Murthy VN. 2016. Population imaging at subcellular resolution supports specific and local inhibition by granule cells in the olfactory bulb. Sci. Rep. 6:29308. doi: 10.1038/srep29308
Gire DH, Kapoor V, Arrighi-Allisan A, Seminara A and Murthy VN. 2016. Mice develop efficient strategies for foraging and navigation using complex natural stimuli. Curr. Biol. 26:1261-1273. doi: 10.1016/j.cub.2016.03.040 [Press: Harvard MCB]
Kapoor V*, Provost AC*, Agarwal P and Murthy VN. 2016. Activation of raphe nuclei triggers rapid and distinct effects on parallel olfactory bulb output channels. Nat Neurosci, 19:271-282, doi:10.1038/nn.4219. (* joint first authors) [Press: Harvard MCB]
2015
Lorenzon P, Redolfi N, Podolsky MJ, Zamparo I, Franchi SA, Pietra G, Boccaccio A, Menini A, Murthy VN, Lodovichi C. 2015. Circuit formation and function in the olfactory bulb of mice with reduced spontaneous afferent activity. J. Neurosci. 35:146-160. doi: 10.1523/JNEUROSCI.0613-14.2015
2014
Rokni D, Murthy VN. 2014. Analysis and synthesis in olfaction. ACS Chem. Neurosci. 5:870-872. doi: 10.1021/c500199n
Rokni D, Hemmelder V, Kapoor V, Murthy VN. 2014. An olfactory cocktail party: figure-ground segregation of odorants in rodents. Nat Neurosci. 17:1225-1232. doi: 10.1038/nn.3775.
Hochbaum DR, Zhao Y, Farhi SL, Klapoetke N, Werley CA, Kapoor V, Zou P, Kralj JM, Maclaurin D, Smedemark-Margulies N, Saulnier JL, Boulting GL, Straub C, Cho YK, Melkonian M, Wong GK, Harrison DJ, Murthy VN, Sabatini BL, Boyden ES, Campbell RE, Cohen AE. 2014. All-optical electrophysiology in mammalian neurons using engineered microbial rhodopsins. Nat Methods. doi: 10.1038/nmeth.3000.
2013
Haddad R, Lanjuin A, Madisen L, Zeng H, Murthy VN, Uchida N. 2013. Olfactory cortical neurons read out a relative time code in the olfactory bulb. Nat Neurosci. 16:949-957. doi:10.1038/nn.3407
Blauvelt DG, Sato TF, Wienisch M, Murthy VN. 2013. Distinct spatiotemporal activity in principal neurons of the mouse olfactory bulb in anesthetized and awake states. Front Neural Circuits. 7:46
2012
Markopoulos F*, Rokni D*, Gire DH, Murthy VN. 2012. Functional properties of cortical feedback projections to the olfactory bulb. Neuron 76(6):1175-88. (* – equal first authors)
Spors H, Albeanu DF, Murthy VN, Rinberg D, Uchida N, Wachowiak M, Friedrich RW. 2012. Illuminating vertebrate olfactory processing. J. Neurosci. 32:14102-8.
Sato T, Murthy VN. 2012. Light-emitting diodes for biological microscopy. Cold Spring Harb Protoc. 2012(12). doi:10.1101/pdb.top072306
Hagiwara A*, Pal SK*, Sato TF, Wienisch M, Murthy VN. 2012. Optophysiological analysis of associational circuits in the olfactory cortex. Front Neural Circuits. 2012;6:18. (* – equal first authors)
Lau CG, Murthy VN. 2012. Activity-dependent regulation of inhibition via GAD67. J. Neurosci. 32:8521-8531.
Wienisch M, Blauvelt DG, Sato TF, Murthy VN. 2012. Two-Photon Imaging of Neural Activity in Awake, Head-Restrained Mice. In: Fellin T, Halassa M Neuronal Network Analysis : Concepts and Experimental Approaches. Humana Press (Springer Protocols) ; 2012. p. pp 45-60.
2011
Isogai Y, Si S, Pont-Lezica L, Tan T, Kapoor V, Murthy VN, Dulac C.2011. Molecular organization of vomeronasal chemoreception. Nature 478:241-5. doi:10.1038/nature10437.
Murthy VN. 2011. Olfactory maps in the brain. Annu Rev Neurosci. 34:233-58.
Dietz SB, Markopoulos F, Murthy VN. 2011. Postnatal development of dendrodendritic inhibition in the mammalian olfactory bulb. Frontiers in Cellular Neuroscience 5:10.
Petzold GC, Murthy VN. 2011. Role of astrocytes in neurovascular coupling. Neuron 71:782-797.
2001-2010
Dhawale AK, Hagiwara A, Bhalla US, Murthy VN*, Albeanu DF*. 2010. Non-redundant odor coding by sister mitral cells revealed by light addressable glomeruli in the mouse. Nat Neurosci. 2010;13:1404-12. (* – joint senior authors)
Qing Q, Pal SK, Tian B, Duan X, Timko BP, Cohen-Karni T, Murthy VN*, Lieber CM*. 2010. Nanowire transistor arrays for mapping neural circuits in acute brain slices. Proc Natl Acad Sci USA. 2010;107:1882-7. (* – joint senior authors)
Petzold GC, Hagiwara A, Murthy VN. 2009. Serotonergic modulation of odor input to the mammalian olfactory bulb. 2009. Nat Neurosci. 12:784-91.
Soucy ER, Albeanu DF, Fantana AL, Murthy VN*, Meister M*. 2009. Precision and diversity in an odor map on the olfactory bulb. Nat Neurosci. 12:210-20. (* – joint senior authors)
Petzold GC, Albeanu DF, Sato TF, Murthy VN. 2008. Coupling of neural activity to blood flow in olfactory glomeruli is mediated by astrocytic pathways. Neuron 2008;58:897-910.
Albeanu DF, Soucy E, Sato TF, Meister M, Murthy VN. 2008. LED arrays as cost effective and efficient light sources for widefield microscopy. PLoS One 3:e2146.
Tyler WJ, Petzold GC, Pal SK, Murthy VN. 2007. Experience-dependent modification of primary sensory synapses in the mammalian olfactory bulb. J Neurosci 27:9427-38.
Newton AJ, Kirchhausen T, Murthy VN. 2006. Inhibition of dynamin completely blocks compensatory synaptic vesicle endocytosis. Proc Natl Acad Sci U S A 103:17955-60.
Hartman KN, Pal SK, Burrone J, Murthy VN. 2006. Activity-dependent regulation of inhibitory synaptic transmission in hippocampal neurons. Nat Neurosci 9:642-9.
Burrone J, Li Z, Murthy VN. 2006. Studying vesicle cycling in presynaptic terminals using the genetically encoded probe synaptopHluorin. Nat Protoc 1:2970-8.
Star EN, Newton AJ, Murthy VN. 2005. Real-time imaging of Rab3a and Rab5a reveals differential roles in presynaptic function. J Physiol 569:103-17.
Dietz SB, Murthy VN. 2005. Contrasting short-term plasticity at two sides of the mitral-granule reciprocal synapse in the mammalian olfactory bulb. J Physiol 569:475-88.
Li Z, Burrone J, Tyler WJ, Hartman KN, Albeanu DF, Murthy VN. 2005. Synaptic vesicle recycling studied in transgenic mice expressing synaptopHluorin. Proc Natl Acad Sci U S A. 2005;102:6131-6.
Tyler WJ, Murthy VN. 2004. Synaptic vesicles. Curr Biol. 14:R294-7.
Burrone J, Murthy VN. 2003. Synaptic gain control and homeostasis. Curr Opin Neurobiol 13:560-7.
Samuel AD, Silva RA, Murthy VN. 2003. Synaptic activity of the AFD neuron in Caenorhabditis elegans correlates with thermotactic memory. J Neurosci 23:373-6.
Murthy VN, De Camilli P. 2003. Cell biology of the presynaptic terminal. Annu Rev Neurosci 26:701-28.
Dertinger SK, Jiang X,Li Z, Murthy VN*, Whitesides GM*. 2002. Gradients of substrate-bound laminin orient axonal specification of neurons. Proc Natl Acad Sci U S A 99:12542-7. (* – joint senior authors)
Burrone J, O’Byrne M, Murthy VN. Multiple forms of synaptic plasticity triggered by selective suppression of activity in individual neurons. Nature 420:414-8.
Star EN, Kwiatkowski DJ, Murthy VN. 2002. Rapid turnover of actin in dendritic spines and its regulation by activity. Nat Neurosci 5:239-46.
Zito K, Murthy VN. 2002. Dendritic spines. Curr Biol 12:R5.
Murthy VN, Schikorski T, Stevens CF, Zhu Y. 2001. Inactivity produces increases in neurotransmitter release and synapse size. Neuron 32:673-82.
Murthy VN. 2001. Spreading synapsins. Nat Neurosci 4:1155-7.
Li Z, Murthy VN. 2001. Visualizing postendocytic traffic of synaptic vesicles at hippocampal synapses. Neuron 31:593-605.
Burrone J, Murthy VN. 2001. Synaptic plasticity: rush hour traffic in the AMPA lanes. Curr Biol 11:R274-7.
Samuel AD, Murthy VN, Hengartner MO. 2001. Calcium dynamics during fertilization in C. elegans. BMC Dev Biol 1:8.
1991-2000
Fetz EE, Chen D, Murthy VN, Matsumura M. 2000. Synaptic interactions mediating synchrony and oscillations in primate sensorimotor cortex. J Physiol Paris 94:323-31.
Murthy VN, Sejnowski TJ, Stevens CF. 2000. Dynamics of dendritic calcium transients evoked by quantal release at excitatory hippocampal synapses. Proc Natl Acad Sci U S A 97:901-6.
Murthy VN. 1999. Getting the membrane into shape for endocytosis. Neuron 24:2-4.
Murthy VN. 1999. Optical detection of synaptic vesicle exocytosis and endocytosis. Curr Opin Neurobiol 9:314-20.
Murthy VN, Stevens CF. 1999. Reversal of synaptic vesicle docking at central synapses. Nat Neurosci 2:503-7.
Zhang B, Ganetzky B, Bellen HJ, Murthy VN. 1999. Tailoring uniform coats for synaptic vesicles during endocytosis. Neuron 23:419-22.
Murthy VN. 1998. Synaptic plasticity: step-wise strengthening. Curr Biol 8:R650-3.
Murthy VN, Stevens CF. 1998. Synaptic vesicles retain their identity through the endocytic cycle. Nature 392:497-501.
Murthy VN. 1997. Synaptic plasticity: neighborhood influences. Curr Biol 7:R512-5.
Murthy VN, Sejnowski, TJ, Stevens CF. 1997. Heterogeneous release properties of visualized individual hippocampal synapses. Neuron 18:599-612.
Murthy VN, Fetz EE. 1996. Synchronization of neurons during local field potential oscillations in sensorimotor cortex of awake monkeys. J Neurophysiol. 76:3968-82.
Murthy VN, Fetz EE. 1996. Oscillatory activity in sensorimotor cortex of awake monkeys: synchronization of local field potentials and relation to behavior. J Neurophysiol. 76:3949-67.
Murthy VN, Fetz EE. 1994. Effects of input synchrony on the firing rate of a three-conductance cortical neuron model. Neural Comp. 6:1111-26.
Murthy VN, Fetz EE. 1992. Coherent 25- to 35-Hz oscillations in the sensorimotor cortex of awake behaving monkeys. Proc Natl Acad Sci U S A. 89:5670-4.
Murthy VN, Marzetta CA, Rudel LL, Zech LA, Foster DM. 1990. Hepatic apo B-100 lipoproteins and plasma LDL heterogeneity in African green monkeys. Am J Physiol. 258(6 Pt 1):E1041-57.
Kushwaha RS, Foster DM, Murthy VN, Carey KD, Bernard MG. 1990. Metabolic regulation of apoproteins of high-density lipoproteins by estrogen and progesterone in thebaboon (Papio sp). Metabolism. 39(5):544-52.
Kushwaha RS, Foster DM, Murthy VN, Carey KD, McGill HC Jr. 1989. Metabolism of larger high density lipoproteins accumulating in some families of baboons fed ahigh cholesterol and high saturated fat diet. J Lipid Res. 30:1147-59.
MurthyLab 